Professor Henderson is a senior staff specialist in Neurology at the Royal Brisbane and Women’s Hospital and The Prince Charles Hospital, and a Professor at the University of Queensland. A graduate of the University of Queensland, he undertook his neurology traineeship at the RBWH. After attaining his fellowship in Neurology from the Royal Australian College of Physicians he continued his studies at the Mayo Graduate School of Medicine in Minnesota, USA, becoming a Senior Neurophysiology Fellow and working at the Mayo Clinic.

He is a member of the Australian Medical Association, the Australian and New Zealand Association of Neurologists, and Co-Director of the RBWH Motor Neurone Disease Multi-Disciplinary Clinic.